Our Framework

How Vantage reads a company — and where every finding comes from

A structured read across clinical, regulatory, technical and commercial questions, with factual claims cited to their sources. It surfaces what the record shows; the decision stays with you.

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8 domains

Grouped into 4 areas and 20 categories

MD + BME

Physician and engineer review on full reports

34 sources

Public records behind every report

24–48h

Delivery after a complete intake

How It Works

From Materials to Report

A full report moves through six stages. The Quick Screen is automated and skips the physician and engineering review.

Step 1 of 6
Submit
Share your materials
Clinical Review
Physician review
Technical Review
Engineering review
Comparables
Public-record peers
Vantage Index
Eight-domain summary
Report
Findings with sources
01
Your Materials
After the NDA, you share company materials by the method we agree. Typical materials include a pitch deck, regulatory filings, clinical data, financial projections and competitive analysis.
Pitch deck & investor materials
FDA submissions & regulatory files
Clinical trial data & publications
Financial projections & cap table
Patent portfolio & IP filings
Manufacturing & quality docs
02
Physician Clinical Review
Arvind Ravinutala, MD, reviews the clinical and regulatory picture: whether the evidence supports the claims, and how the product fits clinical workflow.
Clinical workflow and adoption questions
Evidence and outcomes evaluation
Safety profile on record
Competitive landscape
03
Biomedical Engineering Review
Aswini Ravinutala, BME, reviews technical feasibility, manufacturing and quality readiness, and the IP landscape.
Regulatory pathway
Manufacturing & scalability
IP landscape
Design & quality
04
Comparative Benchmarking
The company is compared with its closest peers among 3,900+ companies in the Vantage substrate, drawn from 34 public sources, so the findings show what comparable companies went through.
3,900+ companies across four verticals
34 public sources, including FDA, SEC, ClinicalTrials.gov, USPTO and CMS
Every figure traceable to its public source
A comparison, not a prediction
05
Vantage Index
Full reports summarize the eight domains in a composite Vantage Index, so companies can be compared on a consistent basis. The Quick Screen has no composite. The index summarizes the record; it is not a verdict or a prediction.
Domain-level findings behind the composite
Sources for each finding
Open questions the record raises
Stage-appropriate comparison from seed to growth
06
Your Report
A report with an executive summary, the eight-domain findings with sources, comparable-company precedents and the open questions the record raises, plus a debrief with the review team.
Executive Summary
Domain Findings
Open Questions
24–48 hours

The 20-Category Assessment Framework

Every full report reads a company across four areas and twenty categories, mapped to the eight domains. We publish the category structure below; the specific scoring criteria and weights remain proprietary.

Clinical & Regulatory

  • · Regulatory pathway viability
  • · Clinical evidence quality
  • · Safety signal assessment
  • · Unmet need alignment
  • · Clinical data maturity
Physician-led review

Technical & IP

  • · IP strength assessment
  • · Technical differentiation
  • · Manufacturing readiness
  • · Supply chain resilience
  • · Quality systems maturity
Engineering-led review

Commercial

  • · Market sizing accuracy
  • · Competitive positioning
  • · Reimbursement pathway
  • · Pricing & market access
  • · Channel distribution
Market & access analysis

Organizational

  • · Management team depth
  • · Financial health
  • · Team completeness
  • · Board & advisor strength
  • · Fundraising trajectory
Team & financial review

The specific evaluation criteria, sub-signals and scoring weights behind each category are proprietary, and are tailored by stage, product class and intended market.

Questions about the framework? Ask on a free 20-minute call. Book a call →

What Sets Us Apart

Beyond Standard Due Diligence

Domain-Level Findings

Each domain in a full report carries its findings and sources, summarized in the composite Vantage Index. The detail behind the number is always there to check.

Questions Worth Pursuing

Findings separate what the record shows from what it leaves open, so you can see which questions warrant further discovery. The decision about what to do stays with you.

Four Areas, One Read

Every full report combines physician and biomedical engineering review with a substrate of 3,900+ comparable life science companies drawn from public records.

Clinical & Regulatory

What does the evidence show? Which pathway and precedent apply? What does the coverage record say? The report sets out the clinical and regulatory record.

Technical & IP

What does manufacturing and quality readiness look like? What does the patent landscape show? Read through a biomedical engineering lens.

Commercial

How do the market assumptions compare with the reimbursement record and comparable companies? The report compares; it does not forecast revenue.

Organizational

What does the record show about the team’s depth, leadership gaps and financing history, compared with companies at the same stage?

Findings anchored to a substrate of 3,900+ companies and 34 public sources. A diagnostic comparison, not an outcome prediction.

Your Assessment Team

The MD + BME Partnership

Every full report is reviewed by our co-founders, a physician and a biomedical engineer. The Quick Screen is automated.

Arvind Ravinutala, MD

Arvind Ravinutala, MD

Co-Founder & Managing Partner

Practicing physician. Chairs a hospital P&T Committee that reviews drugs and devices for adoption; clinical informatics and bioethics committee leadership.

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Aswini Ravinutala, BME

Aswini Ravinutala, BME

Co-Founder & Partner

Biomedical engineer with 10+ years in medical devices at St. Jude Medical, Masimo and Axonics. Reviews manufacturing, quality systems and engineering depth.

Connect

Supported by senior advisor Rinda Sama (former COO, Axonics). Specialist consultation is available when an engagement needs it. Meet the team and see the Spiro Medical disclosure →

Ready to Get a Vantage Assessment?

Quick Screens are delivered within 24 hours and full reports within 48 hours of a complete intake.

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Not sure which report fits? Talk it through on a free 20-minute call. No obligation.

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